SIRT1 links CIITA deacetylation to MHC II activation

SIRT1 links CIITA deacetylation to MHC II activation

Antigen-dependent stimulation of T cells plays a critical role in adaptive immunity and host defense. Activation of major histocompatibility complex II (MHC II) molecules, dictated by Class II transactivator (CIITA), is considered a pivotal step in this process. The mechanism underlying differential...

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Bibliographic Details
Main Authors: Wu, Xiaoyan, Kong, Xiaocen, Chen, Dewei, Li, He, Zhao, Yuhao, Xia, Minjie, Fang, Mingming, Li, Ping, Fang, Fei, Sun, Lina, Tian, Wenfang, Xu, Huihui, Yang, Yuyu, Qi, Xiaohong, Gao, Yuqi, Sha, Jiahao, Chen, Qi, Xu, Yong
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239213/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239213/

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