Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts

Cortical microinfarcts (CMIs) observed in brains of patients with Alzheimer’s disease tend to be located close to vessels afflicted with cerebral amyloid angiopathy (CAA). CMIs in Alzheimer’s disease are preferentially distributed in the arterial borderzone, an area most vulnerable to hypoperfusion....

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Bibliographic Details
Main Authors: Okamoto, Yoko, Yamamoto, Toru, Kalaria, Raj N., Senzaki, Hideto, Maki, Takakuni, Hase, Yoshiki, Kitamura, Akihiro, Washida, Kazuo, Yamada, Mahito, Ito, Hidefumi, Tomimoto, Hidekazu, Takahashi, Ryosuke, Ihara, Masafumi
Format: Online
Language:English
Published: Springer-Verlag 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282897/