RHGF-2 Is an Essential Rho-1 Specific RhoGEF that binds to the Multi-PDZ Domain Scaffold Protein MPZ-1 in Caenorhabditis elegans
RhoGEF proteins activate the Rho family of small GTPases and thus play a key role in regulating fundamental cellular processes such as cell morphology and polarity, cell cycle progression and gene transcription. We identified a Caenorhabditis elegans RhoGEF protein, RHGF-2, as a binding partner of t...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282746/ |