Characterization of the Poly-T Variant in the TOMM40 Gene in Diverse Populations

Characterization of the Poly-T Variant in the TOMM40 Gene in Diverse Populations

We previously discovered that a polymorphic, deoxythymidine-homopolymer (poly-T, rs10524523) in intron 6 of the TOMM40 gene is associated with age-of-onset of Alzheimer's disease and with cognitive performance in elderly. Three allele groups were defined for rs10524523, hereafter ‘523’, based o...

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Main Authors: Linnertz, Colton, Saunders, Ann M., Lutz, Michael W., Crenshaw, Donna M., Grossman, Iris, Burns, Daniel K., Whitfield, Keith E., Hauser, Michael A., McCarthy, Jeanette J., Ulmer, Megan, Allingham, Rand, Welsh-Bohmer, Kathleen A., Roses, Allen D., Chiba-Falek, Ornit
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281049/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281049/

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