African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles

Background: Several studies have demonstrated a lower apolipoprotein E4 (APOE e4) allele frequency in African-Americans, but yet an increased age-related prevalence of AD. An algorithm for prevention clinical trials incorporating TOMM40'523 (Translocase of Outer Mitochondria Membrane) and APOE...

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Bibliographic Details
Main Authors: Roses, A., Lutz, M., Saunders, A., Goldgaber, D., Saul, R., Sundseth, S., Akkari, Patrick, Roses, S., Gottschalk, W., Whitfield, K., Vostrov, A., Hauser, M., Allingham, R., Burns, D., Chiba-Falek, O., Welsh-Bohmer, K.
Format: Journal Article
Published: Elsevier Inc. 2014
Online Access:http://hdl.handle.net/20.500.11937/15480