Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis

ETOC: Caenorhabditis elegans lacking both Ce-emerin and LEM-2 show that these proteins are essential for development of specific lineages, mitosis in somatic cells, and smooth muscle activity. Reduced life span and smooth muscle activity of LEM-2–null worms predicts human LEM2 gene links to diseases...

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Main Authors: Barkan, Rachel, Zahand, Adam J., Sharabi, Kfir, Lamm, Ayelet T., Feinstein, Naomi, Haithcock, Erin, Wilson, Katherine L., Liu, Jun, Gruenbaum, Yosef
Format: Online
Language:English
Published: The American Society for Cell Biology 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279384/
id pubmed-3279384
recordtype oai_dc
spelling pubmed-32793842012-04-30 Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis Barkan, Rachel Zahand, Adam J. Sharabi, Kfir Lamm, Ayelet T. Feinstein, Naomi Haithcock, Erin Wilson, Katherine L. Liu, Jun Gruenbaum, Yosef Articles ETOC: Caenorhabditis elegans lacking both Ce-emerin and LEM-2 show that these proteins are essential for development of specific lineages, mitosis in somatic cells, and smooth muscle activity. Reduced life span and smooth muscle activity of LEM-2–null worms predicts human LEM2 gene links to diseases more severe than Emery-Dreifuss muscular dystrophy. The American Society for Cell Biology 2012-02-15 /pmc/articles/PMC3279384/ /pubmed/22171324 http://dx.doi.org/10.1091/mbc.E11-06-0505 Text en © 2012 Barkan et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0). “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society of Cell Biology.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Barkan, Rachel
Zahand, Adam J.
Sharabi, Kfir
Lamm, Ayelet T.
Feinstein, Naomi
Haithcock, Erin
Wilson, Katherine L.
Liu, Jun
Gruenbaum, Yosef
spellingShingle Barkan, Rachel
Zahand, Adam J.
Sharabi, Kfir
Lamm, Ayelet T.
Feinstein, Naomi
Haithcock, Erin
Wilson, Katherine L.
Liu, Jun
Gruenbaum, Yosef
Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis
author_facet Barkan, Rachel
Zahand, Adam J.
Sharabi, Kfir
Lamm, Ayelet T.
Feinstein, Naomi
Haithcock, Erin
Wilson, Katherine L.
Liu, Jun
Gruenbaum, Yosef
author_sort Barkan, Rachel
title Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis
title_short Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis
title_full Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis
title_fullStr Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis
title_full_unstemmed Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis
title_sort ce-emerin and lem-2: essential roles in caenorhabditis elegans development, muscle function, and mitosis
description ETOC: Caenorhabditis elegans lacking both Ce-emerin and LEM-2 show that these proteins are essential for development of specific lineages, mitosis in somatic cells, and smooth muscle activity. Reduced life span and smooth muscle activity of LEM-2–null worms predicts human LEM2 gene links to diseases more severe than Emery-Dreifuss muscular dystrophy.
publisher The American Society for Cell Biology
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279384/
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