Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis
ETOC: Caenorhabditis elegans lacking both Ce-emerin and LEM-2 show that these proteins are essential for development of specific lineages, mitosis in somatic cells, and smooth muscle activity. Reduced life span and smooth muscle activity of LEM-2–null worms predicts human LEM2 gene links to diseases...
Main Authors: | , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The American Society for Cell Biology
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279384/ |
id |
pubmed-3279384 |
---|---|
recordtype |
oai_dc |
spelling |
pubmed-32793842012-04-30 Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis Barkan, Rachel Zahand, Adam J. Sharabi, Kfir Lamm, Ayelet T. Feinstein, Naomi Haithcock, Erin Wilson, Katherine L. Liu, Jun Gruenbaum, Yosef Articles ETOC: Caenorhabditis elegans lacking both Ce-emerin and LEM-2 show that these proteins are essential for development of specific lineages, mitosis in somatic cells, and smooth muscle activity. Reduced life span and smooth muscle activity of LEM-2–null worms predicts human LEM2 gene links to diseases more severe than Emery-Dreifuss muscular dystrophy. The American Society for Cell Biology 2012-02-15 /pmc/articles/PMC3279384/ /pubmed/22171324 http://dx.doi.org/10.1091/mbc.E11-06-0505 Text en © 2012 Barkan et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0). “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society of Cell Biology. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Barkan, Rachel Zahand, Adam J. Sharabi, Kfir Lamm, Ayelet T. Feinstein, Naomi Haithcock, Erin Wilson, Katherine L. Liu, Jun Gruenbaum, Yosef |
spellingShingle |
Barkan, Rachel Zahand, Adam J. Sharabi, Kfir Lamm, Ayelet T. Feinstein, Naomi Haithcock, Erin Wilson, Katherine L. Liu, Jun Gruenbaum, Yosef Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis |
author_facet |
Barkan, Rachel Zahand, Adam J. Sharabi, Kfir Lamm, Ayelet T. Feinstein, Naomi Haithcock, Erin Wilson, Katherine L. Liu, Jun Gruenbaum, Yosef |
author_sort |
Barkan, Rachel |
title |
Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis |
title_short |
Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis |
title_full |
Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis |
title_fullStr |
Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis |
title_full_unstemmed |
Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis |
title_sort |
ce-emerin and lem-2: essential roles in caenorhabditis elegans development, muscle function, and mitosis |
description |
ETOC: Caenorhabditis elegans lacking both Ce-emerin and LEM-2 show that these proteins are essential for development of specific lineages, mitosis in somatic cells, and smooth muscle activity. Reduced life span and smooth muscle activity of LEM-2–null worms predicts human LEM2 gene links to diseases more severe than Emery-Dreifuss muscular dystrophy. |
publisher |
The American Society for Cell Biology |
publishDate |
2012 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279384/ |
_version_ |
1611505981980672000 |