LEM-3 – A LEM Domain Containing Nuclease Involved in the DNA Damage Response in C. elegans

LEM-3 – A LEM Domain Containing Nuclease Involved in the DNA Damage Response in C. elegans

The small nematode Caenorhabditis elegans displays a spectrum of DNA damage responses similar to humans. In order to identify new DNA damage response genes, we isolated in a forward genetic screen 14 new mutations conferring hypersensitivity to ionizing radiation. We present here our characterizatio...

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Bibliographic Details
Main Authors: Dittrich, Christina M., Kratz, Katja, Sendoel, Ataman, Gruenbaum, Yosef, Jiricny, Josef, Hengartner, Michael O.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285610/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285610/

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