Two Immunoglobulin Tandem Proteins with a Linking β-Strand Reveal Unexpected Differences in Cooperativity and Folding Pathways
The study of the folding of single domains, in the context of their multidomain environment, is important because more than 70% of eukaryotic proteins are composed of multiple domains. The structures of the tandem immunoglobulin (Ig) domain pairs A164–A165 and A168–A169, from the A-band of the giant...
Main Authors: | Steward, Annette, Chen, Qing, Chapman, Robert I., Borgia, Madeleine B., Rogers, Joseph M., Wojtala, Alexsandra, Wilmanns, Matthias, Clarke, Jane |
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Format: | Online |
Language: | English |
Published: |
Elsevier
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277889/ |
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