Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK–p130Cas complex

Targeting of the MT1-MMP protease to focal adhesions by focal adhesion kinase and p130Cas is required for efficient extracellular matrix degradation and tumor cell invasion.

Bibliographic Details
Main Authors: Wang, Yu, McNiven, Mark A.
Format: Online
Language:English
Published: The Rockefeller University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275373/