Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK–p130Cas complex
Targeting of the MT1-MMP protease to focal adhesions by focal adhesion kinase and p130Cas is required for efficient extracellular matrix degradation and tumor cell invasion.
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275373/ |