Growth of Novel Epistatic Interactions by Gene Duplication

Epistasis has long been recognized as fundamentally important in understanding the structure, function, and evolutionary dynamics of biological systems. Gene duplication is a major mechanism of evolution for genetic novelties. Here, we demonstrate that genes evolved significantly more epistatic inte...

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Bibliographic Details
Main Authors: Jiang, Huifeng, Xu, Lin, Gu, Zhenglong
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274824/