Small Molecule Proteostasis Regulators for Protein Conformational Diseases

Small Molecule Proteostasis Regulators for Protein Conformational Diseases

Protein homeostasis (proteostasis) is essential for cellular and organismal health. Stress, aging, and the chronic expression of misfolded proteins, however, challenge the proteostasis machinery and the vitality of the cell. Enhanced expression of molecular chaperones, regulated by heat shock transc...

Full description

Bibliographic Details
Main Authors: Calamini, Barbara, Silva, Maria Catarina, Madoux, Franck, Hutt, Darren M., Khanna, Shilpi, Chalfant, Monica A., Saldanha, Sanjay A., Hodder, Peter, Tait, Bradley D., Garza, Dan, Balch, William E., Morimoto, Richard I.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262058/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262058/

Similar Items