Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192
Transforming growth factor (TGF)-β has been shown to play a central role in the development of tubulointerstitial fibrosis, which can be corrected via treatment with paclitaxel. The biology of microRNA (miR) can be modulated by paclitaxel. We hypothesized that paclitaxel may attenuate renal fibrosis...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
John Wiley & Sons, Ltd.
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258545/ |