Paclitaxel: new uses for an old drug

Paclitaxel (Taxol), one of the most important anticancer drugs, has been used for therapy of different types of cancers. Mechanistically, paclitaxel arrests cell cycle and induces cell death by stabilizing microtubules and interfering with microtubule disassembly in cell division. Recently, it has b...

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Bibliographic Details
Main Authors: Zhang, Dongshan, Yang, Ruhao, Wang, Shixuan, Dong, Zheng
Format: Online
Language:English
Published: Dove Medical Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934593/