Involvement of Akt-1 and mTOR in Sensitivity of Breast Cancer to Targeted Therapy

Involvement of Akt-1 and mTOR in Sensitivity of Breast Cancer to Targeted Therapy

Elucidating the response of breast cancer cells to chemotherapeutic and hormonal based drugs is clearly important as these are frequently used therapeutic approaches. A signaling pathway often involved in chemo- and hormonal-resistance is the Ras/PI3K/PTEN/Akt/mTOR cascade. In the studies presented...

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Bibliographic Details
Main Authors: Sokolosky, Melissa L., Stadelman, Kristin M., Chappell, William H., Abrams, Stephen L., Martelli, Alberto M., Stivala, Franca, Libra, Massimo, Nicoletti, Ferdinando, Drobot, Lyudmyla B., Franklin, Richard A., Steelman, Linda S., McCubrey, James A.
Format: Online
Language:English
Published: Impact Journals LLC 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248182/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248182/

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