Evaluation of Myelotoxicity in Dietary Restricted Rats

The purpose of this study was to clarify the effect of decreased food consumption on evaluation of myelotoxicity in routine general toxicity studies. Male rats were divided into the following 7 groups: 12, 15, and 18 mg/kg 5-fluorouracil (5-FU) treatment groups (FU12, FU15 and FU18); dietary restric...

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Bibliographic Details
Main Authors: Miyata, Hiroto, Asanuma, Fumiko, Iwaki, Yoshinobu, Kimura, Masaaki, Matsumoto, Kiyoshi
Format: Online
Language:English
Published: The Japanese Society of Toxicologic Pathology 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246018/