Assessment of myelotoxicity caused by environmental chemicals.

Potential antineoplastic agents must be screened for the delayed toxicity that occurs in many cases of drug-induced bone marrow aplasia. In vitro clonal assays for hematopoietic progenitor cells have been developed to assess the degree of myelotoxicity. This adverse side effect is often the limiting...

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Bibliographic Details
Main Authors: Boorman, G A, Luster, M I, Dean, J H, Campbell, M L
Format: Online
Language:English
Published: 1982
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568900/