Giant cell arteritis: immune and vascular aging as disease risk factors
Susceptibility for giant cell arteritis increases with chronological age, in parallel with age-related restructuring of the immune system and age-induced remodeling of the vascular wall. Immunosenescence results in shrinkage of the naïve T-cell pool, contraction of T-cell diversity, and impairment o...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239337/ |