The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate

Homeostasis of most adult tissues is maintained by balancing stem cell self-renewal and differentiation, but whether post-transcriptional mechanisms can regulate this process is unknown. Here, we identify that an RNA methyltransferase (Misu/Nsun2) is required to balance stem cell self-renewal and di...

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Bibliographic Details
Main Authors: Blanco, Sandra, Kurowski, Agata, Nichols, Jennifer, Watt, Fiona M., Benitah, Salvador Aznar, Frye, Michaela
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228827/