Titin-Actin Interaction: PEVK-Actin-Based Viscosity in a Large Animal
Titin exhibits an interaction between its PEVK segment and the actin filament resulting in viscosity, a speed dependent resistive force, which significantly influences diastolic filling in mice. While diastolic disease is clinically pervasive, humans express a more compliant titin (N2BA:N2B ratio ~...
| Main Authors: | , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Hindawi Publishing Corporation
2011
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227466/ |