Genome-wide association study identifies susceptibility loci for Dengue shock syndrome at MICB and PLCE1

Hypovolemic shock (Dengue shock syndrome (DSS)), is the commonest life-threatening complication of dengue. We conducted a genome-wide association study of 2,008 pediatric cases treated for DSS and 2,018 controls from Vietnam. Replication of the most significantly associated markers was carried out i...

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Main Authors: Khor, Chiea Chuen, Bich, Chau Tran Nguyen, Pang, Junxiong, Davila, Sonia, Long, Hoang Truong, Ong, Rick T.H., Dunstan, Sarah J., Wills, Bridget, Farrar, Jeremy, Van Tram, Ta, Gan, Tran Thi, Binh, Nguyen Thi Nguyet, Tri, Le Trung, Lien, Le Bich, Tuan, Nguyen Minh, Tham, Nguyen Thi Hong, Lanh, Mai Ngoc, Nguyet, Nguyen Minh, Hieu, Nguyen Trong, Van Vinh Chau, Nguyen, Thuy, Tran Thi, Tan, Dennis E.K., Sakuntabhai, Anavaj, Teo, Yik-Ying, Hibberd, Martin L, Simmons, Cameron P.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223402/