Fast scaffolding with small independent mixed integer programs

Motivation: Assembling genomes from short read data has become increasingly popular, but the problem remains computationally challenging especially for larger genomes. We study the scaffolding phase of sequence assembly where preassembled contigs are ordered based on mate pair data.

Bibliographic Details
Main Authors: Salmela, Leena, Mäkinen, Veli, Välimäki, Niko, Ylinen, Johannes, Ukkonen, Esko
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223363/