Murid Herpesvirus-4 Exploits Dendritic Cells to Infect B Cells

Dendritic cells (DCs) play a central role in initiating immune responses. Some persistent viruses infect DCs and can disrupt their functions in vitro. However, these viruses remain strongly immunogenic in vivo. Thus what role DC infection plays in the pathogenesis of persistent infections is unclear...

Full description

Bibliographic Details
Main Authors: Gaspar, Miguel, May, Janet S., Sukla, Soumi, Frederico, Bruno, Gill, Michael B., Smith, Christopher M., Belz, Gabrielle T., Stevenson, Philip G.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213091/