Vaccination with murid herpesvirus-4 glycoprotein B reduces viral lytic replication but does not induce detectable virion neutralization

Herpesviruses characteristically disseminate from immune hosts. Therefore in the context of natural infection, antibody neutralizes them poorly. Murid herpesvirus-4 (MuHV-4) provides a tractable model with which to understand gammaherpesvirus neutralization. MuHV-4 virions blocked for cell binding b...

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Bibliographic Details
Main Authors: May, Janet S., Stevenson, Philip G.
Format: Online
Language:English
Published: Society for General Microbiology 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052599/