An asymmetric interface between the regulatory particle and core particle of the proteasome

An asymmetric interface between the regulatory particle and core particle of the proteasome

The S. cerevisiae proteasome comprises a 19-subunit regulatory particle (RP) and 28-subunit core particle (CP). To be degraded, substrates must cross the CP-RP interface, a site of complex conformational changes and regulatory events. This interface includes two aligned heteromeric rings: the six AT...

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Bibliographic Details
Main Authors: Tian, Geng, Park, Soyeon, Lee, Min Jae, Huck, Bettina, McAllister, Fiona, Hill, Christopher P., Gygi, Steven P., Finley, Daniel
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210322/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210322/

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