Inhibition of Geranylgeranyl Transferase-I Decreases Cell Viability of HTLV-1-Transformed Cells

Inhibition of Geranylgeranyl Transferase-I Decreases Cell Viability of HTLV-1-Transformed Cells

Human T-cell leukemia virus type-1 (HTLV-1) is the etiological agent of adult T-cell leukemia (ATL), an aggressive and highly chemoresistant malignancy. Rho family GTPases regulate multiple signaling pathways in tumorigenesis: cytoskeletal organization, transcription, cell cycle progression, and cel...

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Bibliographic Details
Main Authors: Edwards, Dustin C., McKinnon, Katherine M., Fenizia, Claudio, Jung, Kyung-Jin, Brady, John N., Pise-Masison, Cynthia A.
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205383/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205383/

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