Orf-I and Orf-II-Encoded Proteins in HTLV-1 Infection and Persistence

The 3′ end of the human T-cell leukemia/lymphoma virus type-1 (HTLV-1) genome contains four overlapping open reading frames (ORF) that encode regulatory proteins. Here, we review current knowledge of HTLV-1 orf-I and orf-II protein products. Singly spliced mRNA from orf-I encodes p12, which can be p...

Full description

Bibliographic Details
Main Authors: Edwards, Dustin, Fenizia, Claudio, Gold, Heather, de Castro-Amarante, Maria Fernanda, Buchmann, Cody, Pise-Masison, Cynthia A., Franchini, Genoveffa
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185781/