Integrins α2β1 and α11β1 regulate the survival of mesenchymal stem cells on collagen I
Although mesenchymal stem cells (MSCs) are the natural source for bone regeneration, the exact mechanisms governing MSC crosstalk with collagen I have not yet been uncovered. Cell adhesion to collagen I is mostly mediated by three integrin receptors – α1β1, α2β1 and α11β1. Using human MSC (hMSC), we...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199721/ |