An Integrated Approach to Elucidate the Intra-Viral and Viral-Cellular Protein Interaction Networks of a Gamma-Herpesvirus

An Integrated Approach to Elucidate the Intra-Viral and Viral-Cellular Protein Interaction Networks of a Gamma-Herpesvirus

Genome-wide yeast two-hybrid (Y2H) screens were conducted to elucidate the molecular functions of open reading frames (ORFs) encoded by murine γ-herpesvirus 68 (MHV-68). A library of 84 MHV-68 genes and gene fragments was generated in a Gateway entry plasmid and transferred to Y2H vectors. All possi...

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Main Authors: Lee, Shaoying, Salwinski, Lukasz, Zhang, Chaoying, Chu, Derrick, Sampankanpanich, Claire, Reyes, Nichole A., Vangeloff, Abbey, Xing, Fangfang, Li, Xudong, Wu, Ting-Ting, Sahasrabudhe, Sudhir, Deng, Hongyu, LaCount, Douglas J., Sun, Ren
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197595/

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