Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies
Glycogen synthase kinase-3 (GSK-3) is ubiquitously expressed and unusually active in resting, non-stimulated cells. In mammals, at least three proteins (α, β1, and β2), generated from two different genes, gsk-3α and gsk-3β, are widely expressed at both the RNA and protein levels although some tissue...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Research Foundation
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186940/ |