AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo

AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo

Neurofibrillary tangles (NFTs) are the pathological hallmark of neurodegenerative diseases commonly known as tauopathies. NFTs result from the intracellular aggregation of abnormally and hyperphosphorylated tau proteins. Tau functions, which include the regulation of microtubules dynamics, are depen...

Full description

Bibliographic Details
Main Authors: Domise, Manon, Didier, Sébastien, Marinangeli, Claudia, Zhao, Haitian, Chandakkar, Pallavi, Buée, Luc, Viollet, Benoit, Davies, Peter, Marambaud, Philippe, Vingtdeux, Valérie
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882625/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882625/

Similar Items