Assaying β-amyloid Toxicity using a Transgenic C. elegans Model

Accumulation of the β-amyloid peptide (Aβ) is generally believed to be central to the induction of Alzheimer's disease, but the relevant mechanism(s) of toxicity are still unclear. Aβ is also deposited intramuscularly in Inclusion Body Myositis, a severe human myopathy. The intensely studied ne...

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Bibliographic Details
Main Authors: Dostal, Vishantie, Link, Christopher D.
Format: Online
Language:English
Published: MyJove Corporation 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185644/