Assaying β-amyloid Toxicity using a Transgenic C. elegans Model

by Dostal, Vishantie, Link, Christopher D.
Published 2010

A semi-automated motion-tracking analysis of locomotion speed in the C. elegans transgenics overexpressing beta-amyloid in neurons

by Machino, Kevin, Link, Christopher D., Wang, Susan, Murakami, Hana, Murakami, Shin
Published 2014

Caenorhabditis elegans as a model system to study post-translational modifications of human transthyretin

by Henze, Andrea, Homann, Thomas, Rohn, Isabelle, Aschner, Michael, Link, Christopher D., Kleuser, Burkhard, Schweigert, Florian J., Schwerdtle, Tanja, Bornhorst, Julia
Published 2016

Soy isoflavone glycitein protects against beta amyloid-induced toxicity and oxidative stress in transgenic Caenorhabditis elegans

by Gutierrez-Zepeda, Astrid, Santell, Ross, Wu, Zhixin, Brown, Marishka, Wu, YanJue, Khan, Ikhlas, Link, Christopher D, Zhao, Baolu, Luo, Yuan
Published 2005

A glycine zipper motif mediates the formation of toxic β-amyloid oligomers in vitro and in vivo

by Fonte, Virginia, Dostal, Vishantie, Roberts, Christine M, Gonzales, Patrick, Lacor, Pascale, Magrane, Jordi, Dingwell, Natalie, Fan, Emily Y, Silverman, Michael A, Stein, Gretchen H, Link, Christopher D
Published 2011

Progranulin regulates neuronal outgrowth independent of Sortilin

by Gass, Jennifer, Lee, Wing C, Cook, Casey, Finch, Nicole, Stetler, Caroline, Jansen-West, Karen, Lewis, Jada, Link, Christopher D, Rademakers, Rosa, Nykjær, Anders, Petrucelli, Leonard
Published 2012

DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans

by Munkácsy, Erin, Khan, Maruf H., Lane, Rebecca K., Borror, Megan B., Park, Jae H., Bokov, Alex F., Fisher, Alfred L., Link, Christopher D., Rea, Shane L.
Published 2016

Utility of an improved model of amyloid-beta (Aβ1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer’s disease

by McColl, Gawain, Roberts, Blaine R, Pukala, Tara L, Kenche, Vijaya B, Roberts, Christine M, Link, Christopher D, Ryan, Timothy M, Masters, Colin L, Barnham, Kevin J, Bush, Ashley I, Cherny, Robert A
Published 2012

Correction: A glycine zipper motif mediates the formation of toxic beta-amyloid oligomers in vitro and in vivo

by Fonte, Virginia, Dostal, Vishantie, Roberts, Christine M, Gonzales, Patrick, Lacor, Pascale N, Velasco, Pauline T, Magrane, Jordi, Dingwell, Natalie, Fan, Emily Y, Silverman, Michael A, Stein, Gretchen H, Link, Christopher D
Published 2014

TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA

by Saldi, Tassa K, Ash, Peter EA, Wilson, Gavin, Gonzales, Patrick, Garrido-Lecca, Alfonso, Roberts, Christine M, Dostal, Vishantie, Gendron, Tania F, Stein, Lincoln D, Blumenthal, Thomas, Petrucelli, Leonard, Link, Christopher D
Published 2014

Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS

by Prudencio, Mercedes, Belzil, Veronique V., Batra, Ranjan, Ross, Christian A., Gendron, Tania F., Pregent, Luc J., Murray, Melissa E., Overstreet, Karen K., Piazza-Johnston, Amelia E., Desaro, Pamela, Bieniek, Kevin F., DeTure, Michael, Lee, Wing C., Biendarra, Sherri M., Davis, Mary D., Baker, Matthew C., Perkerson, Ralph B., van Blitterswijk, Marka, Stetler, Caroline T., Rademakers, Rosa, Link, Christopher D., Dickson, Dennis W., Boylan, Kevin B., Li, Hu, Petrucelli, Leonard
Published 2015