Tropism-Modification Strategies for Targeted Gene Delivery Using Adenoviral Vectors

Tropism-Modification Strategies for Targeted Gene Delivery Using Adenoviral Vectors

Achieving high efficiency, targeted gene delivery with adenoviral vectors is a long-standing goal in the field of clinical gene therapy. To achieve this, platform vectors must combine efficient retargeting strategies with detargeting modifications to ablate native receptor binding (i.e. CAR/integrin...

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Bibliographic Details
Main Authors: Coughlan, Lynda, Alba, Raul, Parker, Alan L., Bradshaw, Angela C., McNeish, Iain A., Nicklin, Stuart A., Baker, Andrew H.
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185574/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185574/

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