The Interaction Between Lentiviral Integrase and LEDGF: Structural and Functional Insights

Since its initial description as an HIV-1 integrase (IN) interactor seven years ago, LEDGF has become one of the best-characterized host factors involved in viral replication. Results of intensive studies in several laboratories indicated that the protein serves as a targeting factor for the lentivi...

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Bibliographic Details
Main Authors: Hare, Stephen, Cherepanov, Peter
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185499/