High Glucose Increases Metallothionein Expression in Renal Proximal Tubular Epithelial Cells

High Glucose Increases Metallothionein Expression in Renal Proximal Tubular Epithelial Cells

Metallothionein (MT) is an intracellular metal-binding, cysteine-rich protein, and is a potent antioxidant that protects cells and tissues from oxidative stress. Although the major isoforms MT-1 and -2 (MT-1/-2) are highly inducible in many tissues, the distribution and role of MT-1/-2 in diabetic n...

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Bibliographic Details
Main Authors: Ogawa, Daisuke, Asanuma, Masato, Miyazaki, Ikuko, Tachibana, Hiromi, Wada, Jun, Sogawa, Norio, Sugaya, Takeshi, Kitamura, Shinji, Maeshima, Yohei, Shikata, Kenichi, Makino, Hirofumi
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179884/

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