High Glucose Increases Metallothionein Expression in Renal Proximal Tubular Epithelial Cells
Metallothionein (MT) is an intracellular metal-binding, cysteine-rich protein, and is a potent antioxidant that protects cells and tissues from oxidative stress. Although the major isoforms MT-1 and -2 (MT-1/-2) are highly inducible in many tissues, the distribution and role of MT-1/-2 in diabetic n...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179884/ |