IGF-1 and Bone: New Discoveries From Mouse Models

Insulin-like growth factor-1 (IGF-1) plays a central role in cellular growth, differentiation, survival, and cell cycle progression. It is expressed early during development and its effects are mediated through binding to a tyrosine kinase receptor, the insulin-like growth factor-1 receptor (IGF-1R)...

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Bibliographic Details
Main Authors: Yakar, Shoshana, Courtland, Hayden-William, Clemmons, David
Format: Online
Language:English
Published: Wiley Subscription Services, Inc., A Wiley Company 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179280/