Adiponectin in Cardiovascular Inflammation and Obesity
Inflammation is widely known to play a key role in the development and progression of cardiovascular diseases. It is becoming increasingly evident that obesity is linked to many proinflammatory and obesity-associated cardiovascular conditions (e.g., metabolic syndrome, acute coronary syndrome, and c...
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SAGE-Hindawi Access to Research
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175407/ |
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pubmed-31754072011-09-22 Adiponectin in Cardiovascular Inflammation and Obesity Aprahamian, Tamar R. Sam, Flora Review Article Inflammation is widely known to play a key role in the development and progression of cardiovascular diseases. It is becoming increasingly evident that obesity is linked to many proinflammatory and obesity-associated cardiovascular conditions (e.g., metabolic syndrome, acute coronary syndrome, and congestive heart failure). It has been observed that adipokines play an increasingly large role in systemic and local inflammation. Therefore, adipose tissue may have a more important role than previously thought in the pathogenesis of several disease types. This review explores the recently described role of adiponectin as an immunomodulatory factor and how it intersects with the inflammation associated with both cardiovascular and autoimmune pathologies. SAGE-Hindawi Access to Research 2011 2011-09-15 /pmc/articles/PMC3175407/ /pubmed/21941676 http://dx.doi.org/10.4061/2011/376909 Text en Copyright © 2011 T. R. Aprahamian and F. Sam. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Aprahamian, Tamar R. Sam, Flora |
| spellingShingle |
Aprahamian, Tamar R. Sam, Flora Adiponectin in Cardiovascular Inflammation and Obesity |
| author_facet |
Aprahamian, Tamar R. Sam, Flora |
| author_sort |
Aprahamian, Tamar R. |
| title |
Adiponectin in Cardiovascular Inflammation and Obesity |
| title_short |
Adiponectin in Cardiovascular Inflammation and Obesity |
| title_full |
Adiponectin in Cardiovascular Inflammation and Obesity |
| title_fullStr |
Adiponectin in Cardiovascular Inflammation and Obesity |
| title_full_unstemmed |
Adiponectin in Cardiovascular Inflammation and Obesity |
| title_sort |
adiponectin in cardiovascular inflammation and obesity |
| description |
Inflammation is
widely known to play a key role in the
development and progression of cardiovascular
diseases. It is becoming increasingly evident
that obesity is linked to many proinflammatory
and obesity-associated cardiovascular conditions
(e.g., metabolic syndrome, acute coronary
syndrome, and congestive heart failure). It has
been observed that adipokines play an
increasingly large role in systemic and local
inflammation. Therefore, adipose tissue may have
a more important role than previously thought in
the pathogenesis of several disease types. This
review explores the recently described role of
adiponectin as an immunomodulatory factor and
how it intersects with the inflammation
associated with both cardiovascular and
autoimmune pathologies. |
| publisher |
SAGE-Hindawi Access to Research |
| publishDate |
2011 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175407/ |
| _version_ |
1611476186642251776 |