Adiponectin in Cardiovascular Inflammation and Obesity
Inflammation is widely known to play a key role in the development and progression of cardiovascular diseases. It is becoming increasingly evident that obesity is linked to many proinflammatory and obesity-associated cardiovascular conditions (e.g., metabolic syndrome, acute coronary syndrome, and c...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
SAGE-Hindawi Access to Research
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175407/ |
| Summary: | Inflammation is
widely known to play a key role in the
development and progression of cardiovascular
diseases. It is becoming increasingly evident
that obesity is linked to many proinflammatory
and obesity-associated cardiovascular conditions
(e.g., metabolic syndrome, acute coronary
syndrome, and congestive heart failure). It has
been observed that adipokines play an
increasingly large role in systemic and local
inflammation. Therefore, adipose tissue may have
a more important role than previously thought in
the pathogenesis of several disease types. This
review explores the recently described role of
adiponectin as an immunomodulatory factor and
how it intersects with the inflammation
associated with both cardiovascular and
autoimmune pathologies. |
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