Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells

PI-3K–mediated repression of FOXO1 and KLF2 promotes proinflammatory cytokine expression by lineage-committed human CCR6+ Th17/Th22 memory cells.

Bibliographic Details
Main Authors: Wan, Qi, Kozhaya, Lina, ElHed, Aimee, Ramesh, Radha, Carlson, Thaddeus J., Djuretic, Ivana M., Sundrud, Mark S., Unutmaz, Derya
Format: Online
Language:English
Published: The Rockefeller University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171088/