A randomized placebo-controlled trial of idebenone in Leber’s hereditary optic neuropathy

Major advances in understanding the pathogenesis of inherited metabolic disease caused by mitochondrial DNA mutations have yet to translate into treatments of proven efficacy. Leber’s hereditary optic neuropathy is the most common mitochondrial DNA disorder causing irreversible blindness in young ad...

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Bibliographic Details
Main Authors: Klopstock, Thomas, Yu-Wai-Man, Patrick, Dimitriadis, Konstantinos, Rouleau, Jacinthe, Heck, Suzette, Bailie, Maura, Atawan, Alaa, Chattopadhyay, Sandip, Schubert, Marion, Garip, Aylin, Kernt, Marcus, Petraki, Diana, Rummey, Christian, Leinonen, Mika, Metz, Günther, Griffiths, Philip G., Meier, Thomas, Chinnery, Patrick F.
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170530/