An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

Epithelial-mesenchymal transition (EMT), a mechanism important for embryonic development, plays a critical role during malignant transformation. While much is known about transcriptional regulation of EMT, alternative splicing of several genes has also been correlated with EMT progression, but the e...

Full description

Bibliographic Details
Main Authors: Shapiro, Irina M., Cheng, Albert W., Flytzanis, Nicholas C., Balsamo, Michele, Condeelis, John S., Oktay, Maja H., Burge, Christopher B., Gertler, Frank B.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158048/