CRISPR–Cas9-mediated genome editing and guide RNA design

by Wiles, Michael V., Qin, Wenning, Cheng, Albert W., Wang, Haoyi
Published 2015

Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells

by Maetzel, Dorothea, Sarkar, Sovan, Wang, Haoyi, Abi-Mosleh, Lina, Xu, Ping, Cheng, Albert W., Gao, Qing, Mitalipova, Maisam, Jaenisch, Rudolf
Published 2014

Casilio: a versatile CRISPR-Cas9-Pumilio hybrid for gene regulation and genomic labeling

by Cheng, Albert W, Jillette, Nathaniel, Lee, Phoebe, Plaskon, Dylan, Fujiwara, Yasuhiro, Wang, Wenbo, Taghbalout, Aziz, Wang, Haoyi
Published 2016

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

by Shapiro, Irina M., Cheng, Albert W., Flytzanis, Nicholas C., Balsamo, Michele, Condeelis, John S., Oktay, Maja H., Burge, Christopher B., Gertler, Frank B.
Published 2011

SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State

by Lodato, Michael A., Ng, Christopher W., Wamstad, Joseph A., Cheng, Albert W., Thai, Kevin K., Fraenkel, Ernest, Jaenisch, Rudolf, Boyer, Laurie A.
Published 2013

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

by Cheng, Albert W, Wang, Haoyi, Yang, Hui, Shi, Linyu, Katz, Yarden, Theunissen, Thorold W, Rangarajan, Sudharshan, Shivalila, Chikdu S, Dadon, Daniel B, Jaenisch, Rudolf
Published 2013

Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease

by Qin, Wenning, Dion, Stephanie L., Kutny, Peter M., Zhang, Yingfan, Cheng, Albert W., Jillette, Nathaniel L., Malhotra, Ankit, Geurts, Aron M., Chen, Yi-Guang, Wang, Haoyi
Published 2015

TALEN-mediated editing of the Mouse Y Chromosome

by Wang, Haoyi, Hu, Yueh-Chiang, Markoulaki, Styliani, Welstead, G. Grant, Cheng, Albert W., Shivalila, Chikdu S., Pyntikova, Tatyana, Dadon, Daniel B., Voytas, Daniel F., Bogdanove, Adam J., Page, David C., Jaenisch, Rudolf
Published 2013

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

by Katz, Yarden, Li, Feifei, Lambert, Nicole J, Sokol, Ethan S, Tam, Wai-Leong, Cheng, Albert W, Airoldi, Edoardo M, Lengner, Christopher J, Gupta, Piyush B, Yu, Zhengquan, Jaenisch, Rudolf, Burge, Christopher B
Published 2014