Nuclear Pore Complex Protein Mediated Nuclear Localization of Dicer Protein in Human Cells

Human DICER1 protein cleaves double-stranded RNA into small sizes, a crucial step in production of single-stranded RNAs which are mediating factors of cytoplasmic RNA interference. Here, we clearly demonstrate that human DICER1 protein localizes not only to the cytoplasm but also to the nucleoplasm....

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Bibliographic Details
Main Authors: Ando, Yoshinari, Tomaru, Yasuhiro, Morinaga, Ayako, Burroughs, Alexander Maxwell, Kawaji, Hideya, Kubosaki, Atsutaka, Kimura, Ryuichiro, Tagata, Maiko, Ino, Yoko, Hirano, Hisashi, Chiba, Joe, Suzuki, Harukazu, Carninci, Piero, Hayashizaki, Yoshihide
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156128/