Stereoselective Inhibition of the hERG1 Potassium Channel
A growing number of drugs have been shown to prolong cardiac repolarization, predisposing individuals to life-threatening ventricular arrhythmias known as Torsades de Pointes. Most of these drugs are known to interfere with the human ether à-gogo related gene 1 (hERG1) channel, whose current is one...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Frontiers Research Foundation
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153011/ |