Capitalizing on Admixture in Genome-Wide Association Studies: A Two-Stage Testing Procedure and Application to Height in African-Americans

As genome-wide association studies expand beyond populations of European ancestry, the role of admixture will become increasingly important in the continued discovery and fine-mapping of variation influencing complex traits. Although admixture is commonly viewed as a confounding influence in associa...

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Bibliographic Details
Main Authors: Kang, Guolian, Gao, Guimin, Shete, Sanjay, Redden, David T., Chang, Bao-Li, Rebbeck, Timothy R., Barnholtz-Sloan, Jill S., Pajewski, Nicholas M., Allison, David B.
Format: Online
Language:English
Published: Frontiers Research Foundation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132882/