The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella

When Salmonella invade mammalian epithelial cells, some populations are surrounded by the autophagy protein LC3. We found that LC3 was recruited in proximity to Salmonella independently of both Atg9L1 and FIP200, which are required for formation of autophagosomes. The dynamics of the ULK1 complex an...

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Bibliographic Details
Main Authors: Kageyama, Shun, Omori, Hiroko, Saitoh, Tatsuya, Sone, Takefumi, Guan, Jun-Lin, Akira, Shizuo, Imamoto, Fumio, Noda, Takeshi, Yoshimori, Tamotsu
Format: Online
Language:English
Published: The American Society for Cell Biology 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128531/