Applications of Different Weighting Schemes to Improve Pathway-Based Analysis
Conventionally, pathway-based analysis assumes that genes in a pathway equally contribute to a biological function, thus assigning uniform weight to genes. However, this assumption has been proved incorrect, and applying uniform weight in the pathway analysis may not be an appropriate approach for t...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Hindawi Publishing Corporation
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114410/ |