Asc-Dependent and Independent Mechanisms Contribute to Restriction of Legionella Pneumophila Infection in Murine Macrophages

Asc-Dependent and Independent Mechanisms Contribute to Restriction of Legionella Pneumophila Infection in Murine Macrophages

The apoptosis-associated speck-like protein containing a caspase recruitment domain (Asc) is an adaptor molecule that mediates inflammatory and apoptotic signals. Legionella pneumophila is an intracellular bacterium and the causative agent of Legionnaire's pneumonia. L. pneumophila is able to c...

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Bibliographic Details
Main Authors: Abdelaziz, Dalia H. A., Gavrilin, Mikhail A., Akhter, Anwari, Caution, Kyle, Kotrange, Sheetal, Khweek, Arwa Abu, Abdulrahman, Basant A., Hassan, Zeinab A., El-Sharkawi, Fathia Z., Bedi, Simranjit S., Ladner, Katherine, Gonzalez-Mejia, M. Elba, Doseff, Andrea I., Mostafa, Mahmoud, Kanneganti, Thirumala-Devi, Guttridge, Dennis, Marsh, Clay B., Wewers, Mark D., Amer, Amal O.
Format: Online
Language:English
Published: Frontiers Research Foundation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112328/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112328/

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