Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centre
The highly processive transcription by multi-subunit RNA polymerases (RNAP) can be interrupted by misincorporation or backtracking events that may stall transcription or lead to erroneous transcripts. Backtracked/misincorporated complexes can be resolved via hydrolysis of the transcript. Here, we sh...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105419/ |